Pharmacology

Drugs Overdose & Treatment

Opiates Naloxone will reverse the effect of opiate overdose, typically in the presence of CNS and respiratory depression. It competitively binds opioid receptors, causing a blockade Usually given IV for fastest action (<1 min) Opioid overdose typically seen in heroin users who have been incarcerated / ‘gone cold turkey’ who subsequently return to heroin abuse. Upon… Continue reading Drugs Overdose & Treatment

Pharmacology

Antibiotic Agents & Mechanisms

Antibiotic Agents & Mechanisms: CLICK TO ENLARGE :   Gram Positive & Negative Bacteria: Drugs used in TB: Rifamycins Inhibits DNA transcription Rifamycin, rifabutin Cidal Nausea, anorexia, pseudomembranous colitis, hepatotoxicity, orange colouration of excreted bodily fluids, toxicity syndromes, drug interactions Also used in mycobacterial infections –these most commonly occur in those with HIV. Resistance prevents… Continue reading Antibiotic Agents & Mechanisms

Opthalmology

Clinical Presentation of CATARACT

Symptoms Glare: When patient looks at a point source of bright light the diffusion of white and colored light around it drastically reduces vision. Night driving becomes especially troublesome. Posterior subcapsular cataract (cupuliform) notably causes disabling glare. Image Blur: Opacification of lens leads to diminution of vision which is characteristically painless and progressive (& does not improve with pin-hole). From a… Continue reading Clinical Presentation of CATARACT